The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2014
Filed:
Jun. 03, 2009
David J. Tweardy, Houston, TX (US);
Xuejun Xu, Missouri City, TX (US);
Moses M. Kasembeli, Houston, TX (US);
David J. Tweardy, Houston, TX (US);
Xuejun Xu, Missouri City, TX (US);
Moses M. Kasembeli, Houston, TX (US);
The United States of America National Institute of Health (NIH), Washington, DC (US);
The United States of America Dept. of Health and Human Services (DHHS), Washington, DC (US);
Abstract
Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further, inhibitors of Stat3 that also do not inhibit Stat1 are described as well as their derivatives. Methods of screening additional compounds for Stat3 inhibition activity and/or non-inhibition of Stat1 activity are also described herein.