The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8778990 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 15, 2014

Filed:

Oct. 29, 2009
Applicants:

Tadashi Honda, Port Jefferson Station, NY (US);

Michael B. Sporn, Tunbridge, VT (US);

Karen T. Liby, West Lebanon, NH (US);

Gordon W. Gribble, Lebanon, NH (US);

Robert M. Kral, Jr., Grapevine, TX (US);

Melean Visnick, Irving, TX (US);

Inventors:

Tadashi Honda, Port Jefferson Station, NY (US);

Michael B. Sporn, Tunbridge, VT (US);

Karen T. Liby, West Lebanon, NH (US);

Gordon W. Gribble, Lebanon, NH (US);

Robert M. Kral, Jr., Grapevine, TX (US);

Melean Visnick, Irving, TX (US);

Assignees:

Trustees of Dartmouth College, Hanover, NH (US);

Reata Pharmaceuticals, Inc., Irving, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/277 (2006.01); A61K 48/00 (2006.01); A61N 5/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention features betulinic acid derivatives having the formula: wherein the variables are defined herein. The invention also provides related compounds and intermediates thereof, as well as pharmaceutical compositions, kits, and articles of manufacture comprising such compounds. Treatment methods and methods of manufacture are also provided.


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