The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2014
Filed:
Mar. 18, 2009
Gregor James Macdonald, Zoersel, BE;
Johannes Wilhelmus John F. Thuring, Antwerpen, BE;
Pauline Carol Stanislawski, Antwerpen, BE;
Wei Zhuang, Antwepen, BE;
Yves Emiel Maria Van Roosbroeck, Heist-op-den-Berg, BE;
Frans Alfons Maria Van Den Keybus, Essen, BE;
Gregor James MacDonald, Zoersel, BE;
Johannes Wilhelmus John F. Thuring, Antwerpen, BE;
Pauline Carol Stanislawski, Antwerpen, BE;
Wei Zhuang, Antwepen, BE;
Yves Emiel Maria Van Roosbroeck, Heist-op-den-Berg, BE;
Frans Alfons Maria Van Den Keybus, Essen, BE;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to 1-aryl-3-aniline-5-alkyl-1,2,4-triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.