The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2014

Filed:

Dec. 22, 2009
Applicants:

Jianqi LI, Xuzhou, CN;

Guan Wang, Xuzhou, CN;

Guisen Zhang, Xuzhou, CN;

Xiangping Yang, Xuzhou, CN;

Peng Xie, Xuzhou, CN;

Linjie Zhang, Xuzhou, CN;

Xiangqing Xu, Xuzhou, CN;

Yumei Wang, Xuzhou, CN;

Inventors:

Jianqi Li, Xuzhou, CN;

Guan Wang, Xuzhou, CN;

Guisen Zhang, Xuzhou, CN;

Xiangping Yang, Xuzhou, CN;

Peng Xie, Xuzhou, CN;

Linjie Zhang, Xuzhou, CN;

Xiangqing Xu, Xuzhou, CN;

Yumei Wang, Xuzhou, CN;

Assignee:

NHWA Pharma, Corporation, Xuzhou, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/496 (2006.01); C07D 295/088 (2006.01); C07D 403/08 (2006.01); C07D 417/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a substituted phenylpiperazine aryl alkanol derivative represented by the following general formula and its salt and hydrate, wherein Cand Crepresent chiral carbon atoms, and the compound is one of the six isomers: (1RS, 2SR), (1RS, 2RS), (1R, 2S), (1S, 2S), (1R, 2R) or (1S, 2R); and R, R, R, Rand Ar are as defined in the specification. The derivative is non-opioid analgesic, has good analgesic effect and relatively small side effects. The invention also relates to a composition comprising the derivative and its use.


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