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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8778412 B1

PDFFull Text
Date of Patent:
Jul. 15, 2014

Filed:

Nov. 05, 2010

Methods for increasing the stabilization of hypoxia inducible factor-1 alpha

Applicants:

Robert Shalwitz, Bexley, OH (US);

Joseph H. Gardner, Cincinnati, OH (US);

Inventors:

Robert Shalwitz, Bexley, OH (US);

Joseph H. Gardner, Cincinnati, OH (US);

Assignee:

Aerpio Therapeutics Inc., Cincinnati, OH (US);

Attorney:

Richard S. Echler

Primary Examiner:

Sean Basquill

Int. Cl.
CPC ...
A61K 33/24 (2006.01); C07D 213/02 (2006.01); A61K 31/541 (2006.01); A61K 31/501 (2006.01); A61K 31/55 (2006.01); A61K 31/4439 (2006.01); A61K 31/44 (2006.01); A61K 31/496 (2006.01); A61K 31/4412 (2006.01); A61K 31/5377 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4412 (2013.01); C07D 213/02 (2013.01); A61K 31/541 (2013.01); A61K 31/501 (2013.01); A61K 31/55 (2013.01); A61K 31/4439 (2013.01); A61K 31/44 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/4545 (2013.01);
Abstract

Disclosed herein are methods for controlling the activity of hypoxia-inducible transcription factor 1-alpha (HIF-1α) and diseases, conditions, or syndromes related thereto, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia. Further disclosed are pharmaceutical compositions comprising HIF-1α prolyl hydroxylase inhibitors useful in treating diseases, conditions, and/or syndromes related thereto the activity of HIF-1α.

Find Patent Forward Citations

Shalwitz, Robert. (2014). Methods for increasing the stabilization of hypoxia inducible factor-1 alpha (U.S. Patent No. 8778412). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8778412

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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