The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2014
Filed:
Jun. 12, 2009
Applicants:
Rea-min Chu, Taipei, TW;
Chien-chun Pai, Taipei, TW;
Tien-fu Chuang, Taipei, TW;
Inventors:
Assignee:
National Taiwan University, Taipei, TW;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2006.01); C12N 5/0784 (2010.01); C12N 5/09 (2010.01); C12N 5/16 (2006.01); C12N 15/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/16 (2013.01); A61K 2039/5154 (2013.01); A61K 39/001 (2013.01); A61K 2039/5152 (2013.01);
Abstract
The present invention provides a dendritic cell-based vaccine by fusing a canine tumor cell and an allogeneic dendritic cell, and a method for preparing the same. The fusion cells expressing canine tumor antigens are generated by fusing canine bone marrow-derived dendritic cells and canine tumor cells. The canine immune system can be induced to produce tumor specific T lymphocytes and natural killer cells when the fusion cells used as a vaccine is injected into a canine body.