The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2014

Filed:

Oct. 28, 2004
Applicants:

Yasuyuki Amoh, San Diego, CA (US);

Lingna LI, San Diego, CA (US);

Meng Yang, San Diego, CA (US);

Ping Jiang, San Diego, CA (US);

Inventors:

Yasuyuki Amoh, San Diego, CA (US);

Lingna Li, San Diego, CA (US);

Meng Yang, San Diego, CA (US);

Ping Jiang, San Diego, CA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); G01N 21/64 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5073 (2013.01);
Abstract

The disclosed invention relates to the observation that nestin expression is a marker for endothelial cell proliferation. Nestin expression is particularly useful as a marker for angiogenesis, particularly for tumor-related angiogenesis. Specifically, nestin serves as an excellent endothelium marker for brain tumors such as gliomas, hemangioblastomas, Schwannomas, medulloblastomas, and meningiomas. Accordingly, the disclosed invention relates to the use of this marker as a basis to model angiogenic activity.


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