The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2014

Filed:

Jul. 29, 2010
Applicants:

Misato Takashima, Kobe, JP;

Miho Shukuri, Kobe, JP;

Miki Goto, Kobe, JP;

Hisashi Doi, Kobe, JP;

Hirotaka Onoe, Kobe, JP;

Masaaki Suzuki, Kobe, JP;

Yasuyoshi Watanabe, Kobe, JP;

Inventors:

Misato Takashima, Kobe, JP;

Miho Shukuri, Kobe, JP;

Miki Goto, Kobe, JP;

Hisashi Doi, Kobe, JP;

Hirotaka Onoe, Kobe, JP;

Masaaki Suzuki, Kobe, JP;

Yasuyoshi Watanabe, Kobe, JP;

Assignee:

Riken, Saitama, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 31/192 (2006.01); A61K 49/04 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 49/0433 (2013.01); A61K 51/0402 (2013.01);
Abstract

Disclosed are: labeled NSAIDs compounds which can be produced within a short time, can be used suitably for a PET method, and enable the imaging of cyclooxygenase-2; and a process for producing the labeled NSAIDs compounds. Specifically disclosed are isotope-labeled 2-arylpropionic acid compounds, each of which is a compound represented by general formula (1) (wherein Ar represents an aryl group which may have a substituent; Rrepresents anyone selected fromCH, CHF and CFF; and Rrepresents a hydrogen atom, or an alkyl group which may have a branch, wherein a compound wherein Ar is a benzene ring, RisCH, and Ris a hydrogen atom is excluded), or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof.


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