The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Jan. 29, 2013
Applicant:

Medarex, Inc., Princeton, NJ (US);

Inventors:

Heng Cheng, Foster City, CA (US);

Sanjeev Gangwar, Foster City, CA (US);

Qiang Cong, Sunnyvale, CA (US);

Assignee:

Medarex, L.L.C., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/00 (2006.01); C07C 235/00 (2006.01); C07C 237/00 (2006.01); C07C 239/00 (2006.01); C07C 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antiproliferative compounds having a structure represented by formula (II), where n, R, R, R, R, and Rare as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:


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