The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Jul. 08, 2010
Applicants:
Thomas Joachim Landewald Rammeloo, Vosselaar, BE;
Ruben DE Keyser, Retie, BE;
Gustaaf Jozef Petrus Schildermans, Balen, BE;
Inventors:
Thomas Joachim Landewald Rammeloo, Vosselaar, BE;
Ruben De Keyser, Retie, BE;
Gustaaf Jozef Petrus Schildermans, Balen, BE;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 409/10 (2006.01); C07D 309/10 (2006.01);
U.S. Cl.
CPC ...
C07D 309/10 (2013.01);
Abstract
The present invention relates to a crystallization procedure to obtain 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.