The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Aug. 30, 2012
Applicants:

Stephan Bachmann, Allschwil, CH;

Alexander Flohr, Loerrach, DE;

Katrin Groebke Zbinden, Liestal, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach BL, CH;

Jens-uwe Peters, Grenzach-Wyhlen, DE;

Markus Rudolph, Basel, CH;

Inventors:

Stephan Bachmann, Allschwil, CH;

Alexander Flohr, Loerrach, DE;

Katrin Groebke Zbinden, Liestal, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach BL, CH;

Jens-Uwe Peters, Grenzach-Wyhlen, DE;

Markus Rudolph, Basel, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 249/04 (2006.01); C07D 233/54 (2006.01); C07D 231/10 (2006.01); C07D 207/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds of formula (I) wherein R, R, R, R, W, X, X, Y, Y, Z and Zare as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used in the treatment of CNS disorders such as schizophrenia, Alzheimer's disease, and Parkinson's disease.


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