The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Jan. 28, 2011
Applicants:

Hongbin Sun, Nanjing, CN;

Jiaqi Shan, Nanjing, CN;

Boyu Zhang, Nanjing, CN;

Fang Yuan, Nanjing, CN;

Inventors:

Hongbin Sun, Nanjing, CN;

Jiaqi Shan, Nanjing, CN;

Boyu Zhang, Nanjing, CN;

Fang Yuan, Nanjing, CN;

Assignee:

Jiangsu Vcare PharmaTech Co. Ltd., Nanjing, Jiangsu Province, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 513/02 (2006.01); C07D 515/02 (2006.01); C07D 409/00 (2006.01); C07D 221/02 (2006.01); A01N 43/42 (2006.01); A61K 31/44 (2006.01); A61K 31/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

Optically active 2-hydroxytetrahydrothienopyridine derivatives represented by Formula I and pharmaceutically acceptable salts, preparation method and use in the manufacture of a medicament thereof are disclosed. The pharmacodynamic experiment results show that the present compounds of Formula I are useful for inhibiting platelet aggregation. The pharmacokinetic experiment results show that the present compound of Formula I can be converted in vivo into pharmacologically active metabolites and are therefore useful for inhibiting platelet aggregation. Therefore, the present compounds are useful for the manufacture of a medicament for preventing or treating thrombosis and embolism related diseases.


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