The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Jan. 25, 2008
Premlata Shankar, El Paso, TX (US);
Sang-kyung Lee, Seoul, KR;
Manjunath Narasimhaswamy, El Paso, TX (US);
Priti Kumar, Hamden, CT (US);
Haoquan Wu, Jamaica Plain, MA (US);
Hong-seok Ban, Seoul, KR;
Premlata Shankar, El Paso, TX (US);
Sang-Kyung Lee, Seoul, KR;
Manjunath Narasimhaswamy, El Paso, TX (US);
Priti Kumar, Hamden, CT (US);
Haoquan Wu, Jamaica Plain, MA (US);
Hong-Seok Ban, Seoul, KR;
Industry-University Cooperation Foundation Hanyang University, Seoul, KR;
Immune Disease Institute, Boston, MA (US);
Abstract
The present invention provides a method of delivering RNA interference molecules to a cell or a cell in a subject, which comprises contacting the cell with a protein-double stranded RNA complex, the complex comprising the double stranded RNA segment containing a double stranded RNA of interest and a protein, the protein comprising (1) a targeting moiety, which will specifically bind to a site on a target cell, and (2) a binding moiety linked thereto, which will bind to the double stranded RNA, wherein the double stranded RNA segment is delivered to a cell and effects RNA interference of the target RNA in the cell.