The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Oct. 07, 2009
Ray R. Radtkey, San Diego, CA (US);
Lance C. Held, San Marcos, CA (US);
Robert B. Wallace, Escondido, CA (US);
Karen Menge, San Diego, CA (US);
David Canter, San Diego, CA (US);
Ray R. Radtkey, San Diego, CA (US);
Lance C. Held, San Marcos, CA (US);
Robert B. Wallace, Escondido, CA (US);
Karen Menge, San Diego, CA (US);
David Canter, San Diego, CA (US);
Gamida for Life B.V., Rotterdam, NL;
Abstract
An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.