The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Feb. 17, 2012
Applicants:

Bertrand Leblond, Paris, FR;

John E. Donello, Dana Point, CA (US);

Cédric Chauvignac, Nogent-sur-Marne, FR;

Thierry Taverne, St. Martin les Boulogne sur Mer, FR;

Eric Beausoleil, Paris, FR;

Anne-sophie Casagrande, Draveil, FR;

Laurent Désiré, Paris, FR;

Matthew P. Pando, Paris, FR;

Rong Yang, Mission Viejo, CA (US);

Inventors:

Bertrand Leblond, Paris, FR;

John E. Donello, Dana Point, CA (US);

Cédric Chauvignac, Nogent-sur-Marne, FR;

Thierry Taverne, St. Martin les Boulogne sur Mer, FR;

Eric Beausoleil, Paris, FR;

Anne-Sophie Casagrande, Draveil, FR;

Laurent Désiré, Paris, FR;

Matthew P. Pando, Paris, FR;

Rong Yang, Mission Viejo, CA (US);

Assignees:

Allergan, Inc., Irvine, CA (US);

Exonhit Therapeutics SA, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/41 (2006.01); C07D 491/00 (2006.01); C07D 498/00 (2006.01); C07D 515/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of the formula wherein R', R, through Rand Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.


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