The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Dec. 17, 2010
Larry Wendell Hardy, Strubridge, MA (US);
Michele L. R. Heffernan, Worcester, MA (US);
Frank Xinhe Wu, Shrewsbury, MA (US);
Kerry L. Spear, Concord, MA (US);
Lakshmi D. Saraswat, Sudbury, MA (US);
Larry Wendell Hardy, Strubridge, MA (US);
Michele L. R. Heffernan, Worcester, MA (US);
Frank Xinhe Wu, Shrewsbury, MA (US);
Kerry L. Spear, Concord, MA (US);
Lakshmi D. Saraswat, Sudbury, MA (US);
Sunovion Pharmaceuticals, Inc., Marlborough, MA (US);
Abstract
Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.