The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Apr. 21, 2011
Se-won Kim, Cheonan-si, KR;
Jung Ho Kim, Cheonan-si, KR;
Se-nyum Kim, Cheonan-si, KR;
Dae-pil Kang, Osan-si, KR;
Youn Ho Han, Gwangju-si, KR;
Guo Fan Jin, Cheonan-si, KR;
Dong-sik Jung, Cheonan-si, KR;
Sung-ho Park, Cheonan-si, KR;
Ji Min Kim, Yangpyeong-gun, KR;
Jhi Zheng, Cheonan-si, KR;
Se-Won Kim, Cheonan-si, KR;
Jung Ho Kim, Cheonan-si, KR;
Se-Nyum Kim, Cheonan-si, KR;
Dae-Pil Kang, Osan-si, KR;
Youn Ho Han, Gwangju-si, KR;
Guo Fan Jin, Cheonan-si, KR;
Dong-Sik Jung, Cheonan-si, KR;
Sung-Ho Park, Cheonan-si, KR;
Ji Min Kim, Yangpyeong-gun, KR;
Jhi Zheng, Cheonan-si, KR;
Oscotech Inc., Cheonan-si, KR;
Abstract
The present invention relates to an alpha-arylmethoxyacrylate derivative, a preparation method thereof and a pharmaceutical composition comprising the same, and the alpha-arylmethoxyacrylate derivative is inhibitory of HIF, which plays an important role in the regulation of genes associated with energy metabolism, vasomotion, angiogenesis and apoptosis and in the response of cells under hypoxic conditions, so that it can be used for preventing or treating of diseases such as cancer, arthritis, psoriasis, diabetic retinopathy and macular degeneration.