The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Mar. 23, 2010
Applicants:

Marina Caldarelli, Milan, IT;

Stefano Adele Nuvoloni, Genoa, IT;

Francesca Quartieri, Arona, IT;

Inventors:

Marina Caldarelli, Milan, IT;

Stefano Adele Nuvoloni, Genoa, IT;

Francesca Quartieri, Arona, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/497 (2006.01); A61K 31/505 (2006.01); C07D 243/08 (2006.01); C07D 403/04 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to substituted pyrrolyl-pyrimidines which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular MPS1. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.


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