The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8772275 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 08, 2014

Filed:

Dec. 12, 2012
Applicant:

Curis, Inc., Lexington, MA (US);

Inventors:

Lee L. Rubin, Wellesley, MA (US);

Oivin Guicherit, San Diego, CA (US);

Stephen Price, Hunsdon Ware, GB;

Edward Andrew Boyd, Berkshire, GB;

Assignee:

Curis, Inc., Lexington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/33 (2006.01); C07D 513/02 (2006.01); C07D 515/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.


Find Patent Forward Citations

Rubin, Lee. (2014). Mediators of hedgehog signaling pathways, compositions and uses related thereto (U.S. Patent No. 8772275). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8772275

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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