The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Jun. 22, 2011
Hae Jin Kim, Daejeon, KR;
Je Wook Lee, Daejeon, KR;
Young Joon Kwon, Daejeon, KR;
Eun Joung Moon, Daejeon, KR;
Hae Jin Kim, Daejeon, KR;
Je Wook Lee, Daejeon, KR;
Young Joon Kwon, Daejeon, KR;
Eun Joung Moon, Daejeon, KR;
Ensoltek Co., Ltd., Daejeon, KR;
Abstract
The present invention provides a peptide represented by formula (I) of X-Leu-X-Leu-Xwherein Xrepresents Glu or Asp, Xrepresents His, Lys or Arg, Xrepresents Asp or Glu, with Glu, Asp, Leu, His, Lys and Arg being respectively glutamic acid, aspartic acid, leucine, histidine, lysine and arginine; or a pharmaceutically acceptable salt thereof; a composition for the treatment or prevention of at least one selected from cartilage damage and arthritis, containing the same peptide or a pharmaceutically acceptable salt thereof as an active ingredient; and a composition containing the same peptide or a pharmaceutically acceptable salt thereof and TGFβ1. The above-mentioned peptide or a pharmaceutically acceptable salt thereof is effective for the treatment and/or prevention of cartilage damage and/or arthritis and is capable of exhibiting effects of the regeneration of cartilage tissue, the inhibition of the expression of cartilage tissue matrix degrading enzyme and/or the inhibition of cartilage tissue ossification.