The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Mar. 01, 2012
Applicants:

Robert J. Twieg, Kent, OH (US);

William E. Moerner, Los Altos, CA (US);

Samuel J. Lord, Palo Alto, CA (US);

NA Liu, Bloomfield, CT (US);

Reichel Samuel, Atlanta, GA (US);

Inventors:

Robert J. Twieg, Kent, OH (US);

William E. Moerner, Los Altos, CA (US);

Samuel J. Lord, Palo Alto, CA (US);

Na Liu, Bloomfield, CT (US);

Reichel Samuel, Atlanta, GA (US);

Assignees:

Kent State University, Kent, OH (US);

Leland Stanford Junior University, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/533 (2006.01); G01N 33/532 (2006.01); C07K 1/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.


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