The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Nov. 15, 2011
Applicant:

Timothy Ragan, Somerville, MA (US);

Inventor:

Timothy Ragan, Somerville, MA (US);

Assignee:

TissueVision, Inc., Somerville, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/30 (2006.01); G01N 33/48 (2006.01); G06K 9/00 (2006.01); A61B 6/00 (2006.01); G01B 9/021 (2006.01); A61B 3/10 (2006.01); G01B 9/02 (2006.01); G01N 21/65 (2006.01);
U.S. Cl.
CPC ...
A61B 3/102 (2013.01); G01B 9/02091 (2013.01); G01N 2021/653 (2013.01); G01N 2223/40 (2013.01);
Abstract

In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging layers of the tissue, sectioning a portion of the tissue, capturing the sectioned tissue, and imaging additional layers of the tissue in a second volume of the tissue, and capturing each portion of sectioned tissue, and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest. Further, captured tissue sections can be processed, re-imaged, and indexed to their original location in the three dimensional image.


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