The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Jun. 28, 2012
Jennifer E. Van Eyk, Baltimore, MD (US);
David Raymond Graham, Arbutus, MD (US);
Rebekah Lynn Gunrdy, Baltimore, MD (US);
Jennifer E. Van Eyk, Baltimore, MD (US);
David Raymond Graham, Arbutus, MD (US);
Rebekah Lynn Gunrdy, Baltimore, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
The present invention relates, e.g., to a method for pre-processing a sample for mass spectral analysis, comprising cleaving proteins in the sample to peptides and immunodepleting highly abundant and/or well-ionizing and/or proteotypic peptides from the sample. Also described are methods for identifying well-ionizing peptides for use in this and other methods; analytic (diagnostic) methods using antibodies against highly ionizable peptides from a protein target of interest; and compositions, kits and devices comprising antibodies of the invention.