The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2014

Filed:

Apr. 15, 2010
Applicants:

Mike Rothe, Krailling, DE;

Martin Treder, München, DE;

Susanne Hartmann, München, DE;

Daniel J. Freeman, Newbury Park, CA (US);

Robert Radinsky, Thousand Oaks, CA (US);

Eric Borges, Maria Enzersdorf, AT;

Inventors:

Mike Rothe, Krailling, DE;

Martin Treder, München, DE;

Susanne Hartmann, München, DE;

Daniel J. Freeman, Newbury Park, CA (US);

Robert Radinsky, Thousand Oaks, CA (US);

Eric Borges, Maria Enzersdorf, AT;

Assignees:

U3 Pharma GmbH, , DE;

Amgen, Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.


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