The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Oct. 18, 2012
Applicants:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Cephalon, Inc., Frazer, PA (US);
Inventors:
Mark I. Greene, Penn Valley, PA (US);
Ramachandran Murali, Drexel Hill, PA (US);
Xin Cheng, Wallingford, PA (US);
Raphael Ottenbrite, Midlothian, VA (US);
Yingxin Xiaio, North Potomac, MD (US);
Assignees:
The Trustees Of The University Of Pennsylvania, Philadelphia, PA (US);
Cephalon, Inc., Wilmingotn, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/15 (2006.01); A61K 31/352 (2006.01); A61K 31/365 (2006.01); C07C 251/86 (2006.01);
U.S. Cl.
CPC ...
C07C 251/86 (2013.01); A61K 31/352 (2013.01); A61K 31/365 (2013.01); A61K 31/15 (2013.01);
Abstract
The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-α mediated conditions.