The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2014

Filed:

Dec. 20, 2013
Applicant:

Dainippon Sumitomo Pharma Co., Ltd., Osaka, JP;

Inventors:

Shinya Usui, Osaka, JP;

Hiroki Yamaguchi, Osaka, JP;

Yoko Nakai, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A medicament for treating diseases associated with cholinergic properties in the central nervous system (CNS) and/or peripheral nervous system (PNS), diseases associated with smooth muscle contraction, endocrine disorders, neurodegenerative disorders and the like, which comprises a compound of Formula (I), wherein A is CRor a nitrogen atom, X—Y—Z is N—CO—NRRand the like, Rto Rare each independently a hydrogen atom and the like, Rto Rare each independently a hydrogen atom and the like, Rand Rare each independently an optionally-substituted C3-10 cycloalkyl and 15 the like, and n is 1 or 2 or a pharmaceutically acceptable salt thereof, which exhibits potent modulatory-effects on the activity of alpha-7 nicotinic acetylcholine receptor (alpha-7 nAChR).


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