The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Mar. 09, 2011
Applicants:
Taisheng Huang, Wilmington, DE (US);
Chu-biao Xue, Hockessin, DE (US);
Hui-yin LI, Hockessin, DE (US);
Qun LI, Newark, DE (US);
Inventors:
Taisheng Huang, Wilmington, DE (US);
Chu-Biao Xue, Hockessin, DE (US);
Hui-Yin Li, Hockessin, DE (US);
Qun Li, Newark, DE (US);
Assignee:
Incyte Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07D 471/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61P 35/00 (2006.01); A61P 29/00 (2006.01); A61P 19/02 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 405/14 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.