The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Jul. 16, 2012
Giyoong Tae, Gwangju, KR;
Bo-young Kim, Gwangju, KR;
Kihak Gwon, Gwanju, KR;
Young Ha Kim, Gwangju, KR;
Myung-han Yoon, Gwangju, KR;
Giyoong Tae, Gwangju, KR;
Bo-young Kim, Gwangju, KR;
Kihak Gwon, Gwanju, KR;
Young Ha Kim, Gwangju, KR;
Myung-Han Yoon, Gwangju, KR;
Gwangju Institute of Science and Technology, Buk-Gu, Gwangju, KR;
Abstract
The present invention relates to a method of modulating a release of biomolecules having heparin-binding affinity, and more specifically, to a method of modulating a release of biomolecules having heparin-binding affinity, using thiolated heparin adsorbed on metal surface. According to the present invention, it is possible to modulate various biomolecules having heparin-binding affinity such as growth factors spatiotemporally by external electrical stimulations, without causing cytotoxicity and having deteriorating effects on cell activity. Thus, the present invention can be applied for various biomedical and biotechnical fields including drug delivery, biosensor, and cell culture.