The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Jun. 15, 2009
Yasuhiro Kajihara, Toyonaka, JP;
Takashi Tsuji, Nagareyama, JP;
Izumi Sakamoto, Tokushima, JP;
Yuri Nambu, Tokushima, JP;
Naohiro Hayashi, Tokushima, JP;
Kazuyuki Ishii, Tokushima, JP;
Kazuhiro Fukae, Tokushima, JP;
Katsunari Tezuka, Tokushima, JP;
Hiroaki Asai, Tokushima, JP;
Yasuhiro Kajihara, Toyonaka, JP;
Takashi Tsuji, Nagareyama, JP;
Izumi Sakamoto, Tokushima, JP;
Yuri Nambu, Tokushima, JP;
Naohiro Hayashi, Tokushima, JP;
Kazuyuki Ishii, Tokushima, JP;
Kazuhiro Fukae, Tokushima, JP;
Katsunari Tezuka, Tokushima, JP;
Hiroaki Asai, Tokushima, JP;
Glytech, Inc., Kyoto, JP;
Abstract
Oligosaccharide chain added GLP-1 peptides are more stable in blood and more active in controlling blood-sugar levels than GLP-1 peptides without added oligosaccharides. Oligosaccharide chain added GLP-1 peptides having GLP-1 activity include at least one or at least two amino acids each substituted with an oligosaccharide chain added amino acid in GLP-1; a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of one or several amino acids; or a GLP-1 analog. Oligosaccharide chain added GLP-1 peptides with at least one amino acid substituted with an oligosaccharide chain added amino acid include an oligosaccharide chain with oligo hyaluronic acid. Oligosaccharide chain added amino acids include oligosaccharide chains attached to amino acids via linkers.