The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Mar. 18, 2005
Hyesook Kim, Bloomfield Hills, MI (US);
Alan A. Dombkowski, Canton, MI (US);
Raymond F. Novak, Orchard Lake, MI (US);
Brian B. Haab, Jenison, MI (US);
Hyesook Kim, Bloomfield Hills, MI (US);
Alan A. Dombkowski, Canton, MI (US);
Raymond F. Novak, Orchard Lake, MI (US);
Brian B. Haab, Jenison, MI (US);
Detroit R&D, Inc., Detroit, MI (US);
Abstract
An antibody microarray screen including a substrate, monoclonal and polyclonal antibodies that are purified immunoglobins, wherein the antibodies are spotted on predetermined positions on the substrate, and fluids unprocessed for immunoglobulin isolation (e.g., anti-sera, ascites fluids, or hybridoma culture media), wherein the unprocessed fluids are spotted on the predetermined positions on the substrate. Production of drug-metabolizing enzyme antibody microarrays containing closely related cytochromes P450 is disclosed. Methods of manufacturing an antibody microarray, an internal control molecule for use in an antibody microarray, a method of determining optimal spotting concentrations of IgG and a method to increase a detectable signal with microarray analysis are disclosed.