The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8765386 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 01, 2014

Filed:

Feb. 14, 2012
Applicants:

Jonathan Zmuda, Germantown, MD (US);

Lance A. Liotta, Bethesda, MD (US);

Gordon Whiteley, Potomac, MD (US);

Inventors:

Jonathan Zmuda, Germantown, MD (US);

Lance A. Liotta, Bethesda, MD (US);

Gordon Whiteley, Potomac, MD (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/576 (2006.01); A61K 39/29 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method and device to detect Hepatitis C (HCV) antibodies in oral fluid is provided. This method introduces a non-antibody detection molecule that labels all classes of patient antibodies in oral fluid, followed by the specific concentration of labeled anti-HCV antibodies by selective capture in a trapping zone consisting of peptide antigens derived from the HCV genome. Signal generated by the labeled antibodies present in the trapping zone is proportional to the number of anti-HCV antibodies bound to the antigens present in the trapping zone. Presence of signal derived from the capture of antibody/detection molecule complexes in the trapping zone is indicative of past exposure to HCV.


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