The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 2014
Filed:
Feb. 25, 2010
Rosario Lizio, Dieburg, DE;
Michael Gottschalk, Ober-Ramstadt, DE;
Michael Damm, Roedermark, DE;
Norbert Windhab, Hofheim, DE;
Melanie Liefke, Ober-Ramstadt, DE;
Guenter Schmitt, Darmstadt, DE;
Erna Roth, Darmstadt, DE;
Ruediger Alexowsky, Nauheim, DE;
Rosario Lizio, Dieburg, DE;
Michael Gottschalk, Ober-Ramstadt, DE;
Michael Damm, Roedermark, DE;
Norbert Windhab, Hofheim, DE;
Melanie Liefke, Ober-Ramstadt, DE;
Guenter Schmitt, Darmstadt, DE;
Erna Roth, Darmstadt, DE;
Ruediger Alexowsky, Nauheim, DE;
Evonik Roehm GmbH, Darmstadt, DE;
Abstract
The invention relates to a pharmaceutical or nutraceutical formulation comprising a core, comprising an active pharmaceutical or nutraceutical ingredient, a penetration promoter and a bioavailability promoting agent, and a polymeric coating for the gastrointestinal targeted release of the active ingredient, characterized in that the bioavailability promoting agent is a pharmaceutically acceptable inhibitor of proteolytic enzymes, which increases the oral bioavailability of the active ingredient by a factor of at least five, compared to a corresponding formulation without the bioavailability promoting agent.