The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2014

Filed:

May. 06, 2005
Applicants:

Svitlana Garbuzova-davis, Tampa, FL (US);

Andrew Balber, Durham, NC (US);

Cyndy Davis-sanberg, Spring Hill, FL (US);

Tracy Gentry, Durham, NC (US);

Nicole Kuzmin-nichols, Brandon, FL (US);

Paul R Sanberg, Spring Hill, FL (US);

Alison Willing, Tampa, FL (US);

Inventors:

Svitlana Garbuzova-Davis, Tampa, FL (US);

Andrew Balber, Durham, NC (US);

Cyndy Davis-Sanberg, Spring Hill, FL (US);

Tracy Gentry, Durham, NC (US);

Nicole Kuzmin-Nichols, Brandon, FL (US);

Paul R Sanberg, Spring Hill, FL (US);

Alison Willing, Tampa, FL (US);

Assignees:

University of South Florida, Tampa, FL (US);

Saneron CCEL Therapeutics, Inc., Tampa, FL (US);

StemCo Biomedical, Inc., Durham, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 35/28 (2006.01); A61K 35/48 (2006.01); A61K 35/12 (2006.01); A61K 35/50 (2006.01); A61K 35/30 (2006.01); A61K 9/00 (2006.01); C12N 5/0789 (2010.01); C12N 5/071 (2010.01); C12N 5/074 (2010.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/51 (2013.01); A61K 2035/124 (2013.01); A61K 35/50 (2013.01); A61K 35/30 (2013.01); A61K 9/0085 (2013.01); C12N 5/0647 (2013.01); C12N 5/0663 (2013.01); C12N 5/0607 (2013.01); C12N 5/0675 (2013.01); C12N 2506/11 (2013.01);
Abstract

A method of treating a patient with a neurodegenerative disease, such as ALS, using progenitor cells isolated from human umbilical cord blood. Non-invasive transplantation of aldehyde dehydrogenase (ALDH) expressing progenitor cells provides cell replacement and protection of motor neurons.


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