The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2014

Filed:

Nov. 11, 2009
Applicants:

Jiafang He, Dayton, NJ (US);

John Bawiec, Wilkes-Barre, PA (US);

Weiguo Liu, Princeton, NJ (US);

Gui-bai Liang, Scotch Plains, NJ (US);

Lihu Yang, Edison, NJ (US);

Inventors:

Jiafang He, Dayton, NJ (US);

John Bawiec, Wilkes-Barre, PA (US);

Weiguo Liu, Princeton, NJ (US);

Gui-Bai Liang, Scotch Plains, NJ (US);

Lihu Yang, Edison, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 209/52 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); A61K 31/403 (2006.01); A61K 31/4184 (2006.01); A61K 31/4192 (2006.01); A61K 31/427 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
Abstract

Described herein are substituted bicyclic amines. In particular, described herein are substituted bicyclic amines that are effective as antagonists of SSTR5 and useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.


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