The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2014

Filed:

Jan. 18, 2008
Applicants:

Yunxiang Zhu, Wayland, MA (US);

Seng H. Cheng, Natick, MA (US);

Canwen Jiang, Southborough, MA (US);

Luis Z. Avila, Arlington, MA (US);

Inventors:

Yunxiang Zhu, Wayland, MA (US);

Seng H. Cheng, Natick, MA (US);

Canwen Jiang, Southborough, MA (US);

Luis Z. Avila, Arlington, MA (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 17/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.


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