The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8759490 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 24, 2014

Filed:

Nov. 01, 2012
Applicant:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Ole Petter Veiby, Westborough, MA (US);

John S. Babcook, Vancouver, CA;

Assignee:

Millennium Pharamaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); C07K 16/00 (2006.01); A61K 51/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3069 (2013.01); C07K 2317/73 (2013.01); A61K 2039/505 (2013.01); G01N 33/57484 (2013.01); C07K 16/00 (2013.01); C07K 2317/77 (2013.01); A61K 51/1072 (2013.01); C07K 2317/34 (2013.01); C07K 2317/21 (2013.01);
Abstract

Antibodies and antigen-binding fragments of antibodies that bind OV064 are disclosed. The antibodies bind an extracellular domain of OV064. Some of the antibodies and antigen-binding fragments bind an epitope on OV064 sufficient to induce internalization. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.


Find Patent Forward Citations

Veiby, Ole. (2014). Antibodies that bind ov064 and methods of use therefor (U.S. Patent No. 8759490). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8759490

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