The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2014

Filed:

Dec. 18, 2009
Applicants:

Theodros Asberom, West Orange, NJ (US);

Xianhai Huang, Warren, NJ (US);

Zhaoning Zhu, Plainsboro, NJ (US);

John W. Clader, Milton, VT (US);

Dmitri A. Pissarnitski, Scotch Plains, NJ (US);

Hubert B. Josien, Jersey City, NJ (US);

Hongmei LI, Warren, NJ (US);

Inventors:

Theodros Asberom, West Orange, NJ (US);

Xianhai Huang, Warren, NJ (US);

Zhaoning Zhu, Plainsboro, NJ (US);

John W. Clader, Milton, VT (US);

Dmitri A. Pissarnitski, Scotch Plains, NJ (US);

Hubert B. Josien, Jersey City, NJ (US);

Hongmei Li, Warren, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (Chemical formula should be inserted here as it appears on abstract in paper form). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).


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