The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Dec. 03, 2010
Applicant:
James L. Sherley, Boston, MA (US);
Inventor:
James L. Sherley, Boston, MA (US);
Assignee:
Boston Biomedical Research Institute, Inc., Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2502/22 (2013.01); C12N 2500/99 (2013.01); C12N 2502/13 (2013.01); C12N 2517/02 (2013.01); C12N 2500/40 (2013.01);
Abstract
Embodied herein are methods of reprogramming somatic cells or tissue stem cells to a more multipotent state or even a pluripotent state, the methods do not involve gene transfer of master transcription factor genes/proteins. The methods are also useful for rapid and efficient cloning of induced pluripotent stem cells after gene transfer of master transcription factor genes/proteins.