The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
May. 07, 2010
Chen-wei Wu, Hsinchu, TW;
Cheng-hsien Liu, Hsinchu, TW;
Chau-ting Yeh, Hsinchu, TW;
Hui-ling Lin, Hsinchu, TW;
Hsin-yu Lai, Hsinchu, TW;
Tzu-chi Yu, Hsinchu, TW;
Chen-Wei Wu, Hsinchu, TW;
Cheng-Hsien Liu, Hsinchu, TW;
Chau-Ting Yeh, Hsinchu, TW;
Hui-Ling Lin, Hsinchu, TW;
Hsin-Yu Lai, Hsinchu, TW;
Tzu-Chi Yu, Hsinchu, TW;
National Tsing Hua University, Hsinchu, TW;
Abstract
Disclosed is a microfluidic chip and method using the same. The microfluidic chip comprises a substrate having a surface, and at least a tissue culture area formed on the surface of the substrate. The tissue culture area has a microfluidic channel formed by a plurality of connected geometrical structures (nozzle-type channels) having a predetermined depth. The microfluidic channel has an inlet and an outlet, which are at two ends of the microfluidic channel, for medium inputting and outputting, respectively. Additionally, at least an air-exchange hole is formed on the bottom of the microfluidic channel. By using the microfluidic chip for tissue culture, lateral flow speed and stress can be decreased, so as to prolong survival time of tissues (e.g. liver tissues).