The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Apr. 07, 2009
Paul D. Bishop, Fall City, WA (US);
Tracey A. Pownder, Seattle, WA (US);
Paul O. Sheppard, Granite Falls, WA (US);
Christopher J. Stenland, Stanwood, WA (US);
Paul D. Bishop, Fall City, WA (US);
Tracey A. Pownder, Seattle, WA (US);
Paul O. Sheppard, Granite Falls, WA (US);
Christopher J. Stenland, Stanwood, WA (US);
Zymogenetics, Inc., Seattle, WA (US);
Abstract
Disclosed are compositions for activating thrombin precursors to thrombin. The compositions provided include polypeptide compositions wherein the pre-pro-sequence comprises a thrombin cleavage site. The compositions provided also include polynucleotides encoding said polypeptides and recombinant systems for expressing said polypeptides. This disclosure also relates to methods for producing said compositions, recovering said compositions, activating said compositions purifying said compositions and producing active thrombin molecules using the active form of said compositions.