The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 24, 2014

Filed:

Jul. 21, 2011
Applicants:

Yiguang Wang, Beijing, CN;

Yang Jiang, Shen Yang, CN;

Shengwu Yang, Shen Yang, CN;

Xiaofeng Zhao, Shen Yang, CN;

Inventors:

Yiguang Wang, Beijing, CN;

Yang Jiang, Shen Yang, CN;

Shengwu Yang, Shen Yang, CN;

Xiaofeng Zhao, Shen Yang, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 19/62 (2006.01); C12P 19/60 (2006.01); C12P 19/44 (2006.01); C12N 1/21 (2006.01); C12R 1/465 (2006.01); C12N 1/20 (2006.01); C12N 15/70 (2006.01); C12N 15/76 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12P 19/62 (2013.01); C12R 1/465 (2013.01); C12N 1/20 (2013.01);
Abstract

A genetically engineered strain WSJ-IA for producing isovaleryl spiramycin I. Also provided is a method for preparing the strain, including the steps of: (a) constructing a recombinant plasmid including a double gene ist-acyB2; (b) transforming the plasmid into an isovaleryl spiramycin I-producing strain to obtain the strain WSJ-IA. The level of isovaleryl spiramycin I produced by fermentation of the strain WSJ-IA is increased 1.7 times and the fermentation potency thereof increased 4.14 times in comparison with the strain exclusively including a single gene ist.


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