The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Feb. 18, 2011
Tomoko Ono, Tokyo, JP;
Shinichiro Watanabe, Kanagawa, JP;
Fumio Furusaki, Tokyo, JP;
Ko Igami, Tokyo, JP;
Tomoko Ono, Tokyo, JP;
Shinichiro Watanabe, Kanagawa, JP;
Fumio Furusaki, Tokyo, JP;
Ko Igami, Tokyo, JP;
Mitsubishi Chemical Medience Corporation, Tokyo, JP;
Juridical Foundation the Chemo-Sero-Therapeutic Research Institute, Kumamoto, JP;
Abstract
A method for determining an appropriate treatment option for a patient who has been diagnosed with disseminated intravascular coagulation (DIC) but who may have thrombotic thrombocytopenic purpura (TTP), by analyzing the amount and/or enzyme activity of a von Willebrand factor (vWF)-cleaving protease (ADAMTS13) and the amount of vWF in a patient that has been diagnosed with DIC is disclosed. Using the method of the present invention, a differential diagnosis of patients with thrombotic thrombocytopenic purpura (TTP) can be made from among patients diagnosed with DIC, which could not previously be distinguished on the basis of only clinical findings or known markers. Also disclosed is a kit for determining an appropriate treatment option, the kit comprising an antibody or a fragment thereof which specifically binds to ADAMTS13.