The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Jan. 29, 2010
Andreas R. Huber, Aarau, CH;
Luca Bernasconi, Zurich, CH;
Roberto Herklotz, Lugano, CH;
Saskia Brunner-agten, Bern, CH;
Andreas R. Huber, Aarau, CH;
Luca Bernasconi, Zurich, CH;
Roberto Herklotz, Lugano, CH;
Saskia Brunner-Agten, Bern, CH;
Kantonsspital Aarau AG, Aarau, CH;
Abstract
The present invention relates to methods of detecting the presence of a genetic polymorphism within two or more closely linked, homologous genes, for example α-thalassemia, in a sample using RT-PCR by subjecting the sample to separate amplification reactions using (a) a pair of forward and reverse primers specific for the head region of each of said two or more closely linked, homologous genes and (b) a pair of forward and reverse primers specific for the tail region of each of said two or more closely linked, homologous genes; and detecting and quantitating the amplification products relative to a control product.