The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Mar. 19, 2008
Toshiro Shirakawa, Hyogo, JP;
Masato Kawabata, Hyogo, JP;
Tetsuo Takata, Hyogo, JP;
Michiko Taniguchi, Hyogo, JP;
Asako Okamoto, Hyogo, JP;
Masanori Asada, Osaka, JP;
Masaaki Nakatsuji, Osaka, JP;
Toshiro Shirakawa, Hyogo, JP;
Masato Kawabata, Hyogo, JP;
Tetsuo Takata, Hyogo, JP;
Michiko Taniguchi, Hyogo, JP;
Asako Okamoto, Hyogo, JP;
Masanori Asada, Osaka, JP;
Masaaki Nakatsuji, Osaka, JP;
Morishita Jintan Co., Ltd., Osaka, JP;
Abstract
The present invention provides an oral vaccine against a bacterial infectious disease (e.g., typhoid fever, cholera, or dysentery). The oral vaccine of the present invention is a capsule formulation in which a transformed microorganism that expresses a flagellin antigen protein or that secretes a flagellin antigen protein out of the cell of the microorganism is encapsulated with an acid-resistant membrane. Examples of the microorganism include intestinal bacteria belonging to the genus, the genus, the genus, and the like. The form of the capsule formulation may be any one of a seamless capsule formulation, a soft capsule formulation, and a hard capsule formulation.