The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Mar. 16, 2012
Carmen Barske, Loerrach, DE;
Stefan Frentzel, Lörrach, DE;
Anis Khurso Mir, Bartenheim, FR;
Martin E. Schwab, Zürich, CH;
Alessandra Vitaliti Garami, Oberwill, CH;
Carmen Barske, Loerrach, DE;
Stefan Frentzel, Lörrach, DE;
Anis Khurso Mir, Bartenheim, FR;
Martin E. Schwab, Zürich, CH;
Alessandra Vitaliti Garami, Oberwill, CH;
Novartis AG, Basel, CH;
Abstract
The present invention provides a binding molecule which is capable of binding to the human NogoA polypeptide or human NiG with a dissociation constant <1000 nM, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system; a pharmaceutical composition comprising said binding molecule; and a method of treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system.