The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Dec. 16, 2009
Theoharis V. Koftis, Salonika, GR;
Ioanna Georgopoulou, Salonika, GR;
Alexandros Strongilos, Koropi Attikis, GR;
Fotini Liepouri, Koropi Attikis, GR;
Theodoros Panagiotidis, Salonika, GR;
Alexandra Lithadioti, Salonika, GR;
Theoharis V. Koftis, Salonika, GR;
Ioanna Georgopoulou, Salonika, GR;
Alexandros Strongilos, Koropi Attikis, GR;
Fotini Liepouri, Koropi Attikis, GR;
Theodoros Panagiotidis, Salonika, GR;
Alexandra Lithadioti, Salonika, GR;
Pharmathen S.A., Pallini Atikis, GR;
Abstract
The present invention relates to a novel process for the preparation of O-desmethyl venlafaxine (ODV) and the pharmaceutically acceptable salts thereof, wherein it comprises (i) provision of spiro-venlafaxine compound as intermediate; (ii) conversion of spiro-venlafaxine intermediate into ODV free base in a one-pot process; and (iii) optionally conversion ODV free base into pharmaceutically acceptable salts. The present invention further relates to novel processes for the preparation of crystalline salts of ODV-succinate and ODV-oxalate.