The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2014

Filed:

Nov. 16, 2012
Applicant:

Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);

Inventors:

Narendra Bhalchandra Ambhaikar, Hyderabad, IN;

Robert Hughes, San Diego, CA (US);

Dennis James Hurley, San Marcos, CA (US);

Elaine Chungmin Lee, Cambridge, MA (US);

Benjamin Littler, Carlsbad, CA (US);

Mehdi Numa, San Diego, CA (US);

Stefanie Roeper, Medford, MA (US);

Urvi Sheth, San Diego, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith.


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