The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2014

Filed:

Jun. 27, 2011
Applicants:

Jon E. Chatterton, Forth Worth, TX (US);

Abbot F. Clark, Arlington, TX (US);

David P. Bingaman, Weatherford, TX (US);

Martin B. Wax, Westlake, TX (US);

Adrian M. Timmers, Forth Worth, TX (US);

Inventors:

Jon E. Chatterton, Forth Worth, TX (US);

Abbot F. Clark, Arlington, TX (US);

David P. Bingaman, Weatherford, TX (US);

Martin B. Wax, Westlake, TX (US);

Adrian M. Timmers, Forth Worth, TX (US);

Assignee:

Alcon Research, Ltd, Fort Worth, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

RNA interference is provided for inhibition of tumor necrosis factor α (TNFα) by silencing TNFα cell surface receptor TNF receptor-1 (TNFR1) mRNA expression, or by silencing TNFα converting enzyme (TACE/ADAM17) mRNA expression. Silencing such TNFα targets, in particular, is useful for treating patients having a TNFα-related condition or at risk of developing a TNFα-related condition, such as ocular angiogenesis, retinal ischemia, and diabetic retinopathy.


Find Patent Forward Citations

Chatterton, Jon. (2014). Rnai-related inhibition of tnfα signaling pathway for treatment of ocular angiogenesis (U.S. Patent No. 8754202). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8754202

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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