The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Jan. 05, 2011
Mojca Lunder, Ljubljana, SI;
Matjaz Ravnikar, Ljubljana, SI;
Borut Strukelj, Ljubljana, SI;
Ales Berlec, Ziri, SI;
Boris Ceh, Ljubljana, SI;
Mojca Lunder, Ljubljana, SI;
Matjaz Ravnikar, Ljubljana, SI;
Borut Strukelj, Ljubljana, SI;
Ales Berlec, Ziri, SI;
Boris Ceh, Ljubljana, SI;
University of Ljubljana, Ljubljana, SI;
Institute Jozef Stefan, Ljubljana, SI;
Labena d.o.o., Ljubljana, SI;
Abstract
The present invention relates to microorganisms that express, or have attached to their surface, a TNFα binding polypeptide. Peptides expressed or attached on the surface of microorganism are more resistant to chemical and enzymatic degradation in the gastrointestinal tract. Such microorganisms are capable of binding TNFα and therefore reducing the content of free TNFα and alleviating its pro-inflammatory effects in the gut. The invention also relates to the use of such microorganisms as medicament in the treatment of inflammatory bowel disease.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile