The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Nov. 16, 2007
Dawn M. George, Charlton, MA (US);
Richard W. Dixon, Jefferson, MA (US);
Michael Friedman, Newton, MA (US);
Adrian D. Hobson, Shrewsbury, MA (US);
Biqin LI, Northborough, MA (US);
LU Wang, Northborough, MA (US);
Xiaoyun Wu, Westborough, MA (US);
Neil Wishart, Jefferson, MA (US);
Dawn M. George, Charlton, MA (US);
Richard W. Dixon, Jefferson, MA (US);
Michael Friedman, Newton, MA (US);
Adrian D. Hobson, Shrewsbury, MA (US);
Biqin Li, Northborough, MA (US);
Lu Wang, Northborough, MA (US);
Xiaoyun Wu, Westborough, MA (US);
Neil Wishart, Jefferson, MA (US);
AbbVie Inc., North Chicago, IL (US);
Abstract
The present invention is directed to novel aminopyrrolidines of formula I pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, stereoisomers thereof or pro-drugs thereof, wherein the variables are as defined herein. The compounds of formula (I) are useful as chemokine receptor antagonists and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.